I’ve had that happen several times over the past few days. When it does, I found that I can get things working again by going to the “Edit My Profile” link, then back to the PowerShell.org main site afterward. No idea what causes it. It’s not always when I first open the site; I’ve had this condition appear when I was submitting a forum post (which would have been very annoying, except when I clicked “Back” in the browser, all the text was saved).
I’ll try to remember to save off a copy if I see it again.